Demonstration of Anti-Inflammatory and Metabolic Stability Assay of Andrographis Paniculata
نویسندگان
چکیده
منابع مشابه
An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide
BACKGROUND The anti-inflammatory activity of Andrographis paniculata (Acanthaceae), a traditional medicine widely used in Asia, is commonly attributed to andrographolide, its main secondary metabolite. Commercial A. paniculata extracts are standardised to andrographolide content. We undertook the present study to investigate 1) how selective enrichment of andrographolide in commercial A. panicu...
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The chloroform extract of Andrographis paniculata roots was tested for its antihyperglycemic activity in alloxan induced diabetic rats using chronic and acute studies. The blood glucose lowering activity was determined after oral administration at doses of 50, 100 and 150 mg/kg body weight in acute study. Where as in case of chronic study blood glucose, protein, albumin and creatinine levels ...
متن کاملStability of Andrographolide in Andrographis Paniculata under Selected Storage Conditions
Fresh Andrographis paniculata was dried by a thin layer drying technique using hot air at a temperature of 55°C and velocity of 1.0 m/s. The dried sample was then ground and kept in air-tight glass bottles at three selected storage conditions (5±2°C; 25±2°C with 60% ± 5% RH; 30±2°C with (60% ± 5%RH) for three months period. The contents of the active compound andrographolide present in the drie...
متن کاملAP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata
Andrographolide (AG) is an abundant component of plants of the genus Andrographis and has a number of beneficial properties including neuroprotective, anticancer, anti-inflammatory, and antidiabetic effects. Despite numerous pharmacological studies, the precise mechanism of AG is still ambiguous. Thus, in the present study, we investigated the molecular mechanisms of AG and its target proteins ...
متن کاملAnti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats.
Andrographis paniculata is an annual herb and widely cultivated in Southeast Asian countries for its medicinal use. In recent investigations, A. paniculata was found to be effective against Type 1 diabetes mellitus (Type 1 DM). Here, we used a non-genetic out-bred Sprague-Dawley rat model to test the antidiabetic activity of A. paniculata against Type 2 diabetes mellitus (Type 2 DM). Proton Nuc...
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ژورنال
عنوان ژورنال: International Journal for Research in Applied Science and Engineering Technology
سال: 2018
ISSN: 2321-9653
DOI: 10.22214/ijraset.2018.5236